EGFR Fc Chimera Protein, Rhesus macaque
SKU: 61075206532

EGFR Fc Chimera Protein, Rhesus macaque

Sale price$252.00 Regular price$280.00
Save 10%

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 6 - Jul 11

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

EGFR Fc Chimera Protein, Rhesus macaqueProduct Specification Species Rhesus macaque Synonyms ERBB,ERRP,HER1,mENA,ERBB1 Accession P55245 Amino Acid Sequence Leu25 Ser645, with C terminal Human IgG1 Fc

Product Specification


Species Rhesus macaque
Synonyms ERBB,ERRP,HER1,mENA,ERBB1
Accession P55245
Amino Acid Sequence

Leu25-Ser645, with C-terminal Human IgG1 Fc

LEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSEFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSSQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCQNVSRGRECVDKCNVLEGEPREFVENSECIQCHPECLPQVMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCARNGPKIPSIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Expression System HEK293
Molecular Weight 115-125kDa (Reducing)
Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag Human Fc Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

The Epidermal Growth Factor Receptor (EGFR)is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

 EGFR is activated after homodimerization or heterodimerization. Heterodimerization is an important mechanism that allows the activation of all EGFR in response to ligand stimulation. The activated EGFR binds to many signaling proteins and stimulates the activation of many signaling pathways. The specificity and potency of intracellular signaling pathways are determined by positive and negative regulators, the specific composition of activating ligand(s), receptor dimer components, and the diverse range of proteins that associate with the tyrosine phosphorylated C-terminal domain of the EGFR.EGFR is overexpressed or mutated in many cancers, especially in breast cancer, ovarian cancer, and non-small cell lung cancer. The overexpression and overactivation of EGFR is correlated with poor prognosis, drug resistance, cancer metastasis, and lower survival rate.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 61075206532

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.1 ★★★★★
Based on 891 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
S
Verified Purchase
SRF
San Leandro, US
★★★★★ 4
Great Hold-All
This seems to be well-made and I like the configuration. It should hold passport, ID, credit cards, cash and any travel docs with no problem. It is a bit larger than I expected, however, so that will have an impact on what sort of purse, belt bag, or etc. I use to carry it. My biggest issue with this and ANY RFID blocking wallets/purses/etc. is that I wish the manufacturers would add a sewn in tag or imprint on the product itself that SAYS it's RFID blocking. After time goes buy it gets hard to remember which items in your travel stash are or aren't. I've used a Sharpie to mark this one, but it would be nice if the manufacturer did so professionally.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 5, 2024
A
Verified Purchase
Alex
Phoenix, US
★★★★★ 5
Passport wallet
Perfect for travel and daily life .Holds everything you need and has extra room for ID, driver's license, etc..zipper closure. Love it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 11, 2025
Z
Verified Purchase
Zachary S
Massapequa, US
★★★★★ 5
Convenient for international travel
The Amazon Basics Travel Passport Wallet Organizer is an essential tool for any traveler seeking organization and security. Designed with practicality in mind, this wallet excels at holding passports securely, ensuring that your most important document is always accessible and protected. This is particularly useful for families or groups traveling together, as it can accommodate multiple passports without becoming cumbersome. One of the standout features of this organizer is its ability to keep any receipts you may accumulate on your journey. This is incredibly handy for customs, where having a record of your purchases can streamline the process and prevent any unnecessary delays. The wallet's multiple pockets are thoughtfully designed, providing organized sections not just for receipts, but also for boarding passes, credit cards, and even a pen—making it a comprehensive travel companion. The quality of the Amazon Basics Travel Passport Wallet Organizer is apparent in its durable material and sturdy construction, promising longevity and resilience against the rigors of travel. Its compact size allows for easy storage in a carry-on bag or backpack, yet it doesn't sacrifice space or functionality. In summary, the Amazon Basics Travel Passport Wallet Organizer is a reliable, well-designed product that addresses the needs of modern travelers. Its capacity to securely hold passports, organize receipts for customs, and provide multiple pockets for various essentials makes it an invaluable asset for anyone looking to travel with ease and efficiency.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 7, 2024
K
Verified Purchase
King C
Chelsea, US
★★★★★ 5
Great Value
Good quality, great value! A little big for my use.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 5, 2026
T
Verified Purchase
TootsieEdwards
Fort Morgan, US
★★★★★ 5
The most complete, compact wallet I've ever seen!!
This is the most complete, compact wallet I have ever seen, there is a space for everything, even coins. I ordered 2, one for me and one for him. Mine does not fit in my purse, it's 10 inches long. I'm debating, should I return mine or keep it. I've searched for one similar, less than 10 inches, and found nothing. He is so excited and happy, he has already filled his up. This is the only wallet one needs AND it's RFID blocking.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 18, 2026

recommand products