Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 7 - Jul 12
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
PD-L2/B7-DC His Tag Protein, MouseProduct Specification Species Mouse Synonyms PDL2, PD L2, Butyrophilin B7 DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2 Accession Q9WUL5 Amino Acid Sequence Leu20 Arg219, with C terminal 8*His LFTVTAPKEVYTVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSLQSERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPRGGGSHHHHHHHH Expression System HEK293 Molecular Weight 32 43kDa
Product Specification
| Species | Mouse |
| Synonyms | PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2 |
| Accession | Q9WUL5 |
| Amino Acid Sequence | Leu20-Arg219, with C-terminal 8*His LFTVTAPKEVYTVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSLQSERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPRGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 32-43kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Kojima M. et al. (2014) Fusion Protein of Mutant B7-DC and Fc Enhances the Antitumor Immune Effect of GM-CSF-secreting Whole-cell Vaccine. J Immunother. 37(3): 147-154. |
Background
B7-DC [also known as programmed death ligand 2 (PD-L2)] is a costimulatory molecule expressed predominantly on dendritic cells (DCs) and macrophages. In addition to its coinhibitory receptor, programmed death receptor 1 (PD-1), evidence suggests that B7-DC interacts with an unidentified costimulatory receptor on T cells. B7-DC mutants with selective binding capacity for the costimulatory receptor may be effective in stimulating antitumor immune responses, while avoiding the inhibitory effects of PD-1.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.4 ★★★★★
Based on 1092 reviews
Sort
Product Reviews
★★★★★ 4
Gou has done it again.
Format: Paperback
I like the original text, I love the adaptation because it doesn't stray too far from it. The illustration is beautiful and sometimes gross (In a good way, I mean it's a cosmic horror about people turning into fish, maybe don't read it right before a meal or before bed.)
Gou Tanabe has been working through many of H.P Lovecraft's more popular or interesting stories and this one is just about as good as the rest. The translation as always is very good throughout with only one or two "Wait, what?" moments which could have come from reading the original text differently.
I definitely recommend this book and several of others from Gou Tanabe if you love cosmic horror, manga, or H.P Lovecraft.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 9, 2025
★★★★★ 5
An Eldritch Tale Deserving the Manga Treatment
Format: Paperback
One of Lovecraft's very best (and my personal favourite of his macabre tales), rendered in grotesque mana style. While it doesn't eclipse its inspiration, I thoroughly enjoyed this unique take on a classic tale.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 13, 2026
★★★★★ 5
HP fans will love it
Format: Paperback
Awesome book a must have
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 12, 2026
★★★★★ 5
Great book
Format: Hardcover
Keeps children and adults even interested. My little one wants to read over and over again. It’s very cool and educational which I love. It sparks the love of science and learning.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 10, 2026
★★★★★ 5
Beautiful book 📕
Format: Hardcover, Format: Hardcover
My 6 years son love it 🥰. He really enjoys looking every detail and lifting flaps. Excellent quality. I strongly recommend it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 23, 2025